Involvement of WAVE Accumulation in Aβ/APP Pathology-Dependent Tangle Modification in Alzheimer’s Disease

Synaptic deficits are closely correlated with cognitive dysfunction in Alzheimer’s disease (AD), and synaptic integrity is regulated by the actin cytoskeleton. We demonstrated here that the Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE), a key molecule for actin assembly...

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Detalhes bibliográficos
Main Authors: Takata, Kazuyuki, Kitamura, Yoshihisa, Nakata, Yukinori, Matsuoka, Yasuji, Tomimoto, Hidekazu, Taniguchi, Takashi, Shimohama, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708790/
https://ncbi.nlm.nih.gov/pubmed/19497998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080908
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