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Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca(2+) release in smooth muscle

Membrane depolarization activates voltage-dependent Ca(2+) channels (VDCCs) inducing Ca(2+) release via ryanodine receptors (RyRs), which is obligatory for skeletal and cardiac muscle contraction and other physiological responses. However, depolarization-induced Ca(2+) release and its functional imp...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Liu, Qing-Hua, Zheng, Yun-Min, Korde, Amit S., Yadav, Vishal R., Rathore, Rakesh, Wess, Jürgen, Wang, Yong-Xiao
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708720/
https://ncbi.nlm.nih.gov/pubmed/19549818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813307106
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