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Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca(2+) release in smooth muscle
Membrane depolarization activates voltage-dependent Ca(2+) channels (VDCCs) inducing Ca(2+) release via ryanodine receptors (RyRs), which is obligatory for skeletal and cardiac muscle contraction and other physiological responses. However, depolarization-induced Ca(2+) release and its functional imp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708720/ https://ncbi.nlm.nih.gov/pubmed/19549818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813307106 |
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