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The Nucleocapsid Region of Human Immunodeficiency Virus Type 1 Gag Assists in the Coordination of Assembly and Gag Processing: Role for RNA-Gag Binding in the Early Stages of Assembly

Human immunodeficiency virus type 1 (HIV-1) Gag-RNA interactions are required for virus assembly. However, our prior study found that a defect in particle production exhibited by an HIV-1 proviral mutant with a severe deletion in the RNA-binding nucleocapsid (NC) region of Gag, NX, could be reversed...

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Main Authors: Ott, David E., Coren, Lori V., Shatzer, Teresa
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708646/
https://ncbi.nlm.nih.gov/pubmed/19457986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00099-09
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