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Redundant Roles for Nucleocapsid and Matrix RNA-Binding Sequences in Human Immunodeficiency Virus Type 1 Assembly

RNA appears to be required for the assembly of retroviruses. This is likely due to binding of RNA by multiple Gags, which in turn organizes and stabilizes the Gag-Gag interactions that form the virion. While the nucleocapsid (NC) domain is the most conspicuous RNA-binding region of the human immunod...

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Detalles Bibliográficos
Main Authors: Ott, David E., Coren, Lori V., Gagliardi, Tracy D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280203/
https://ncbi.nlm.nih.gov/pubmed/16254319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13839-13847.2005
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