Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

The innate immune system of humans recognizes the human pathogenic fungus Candida albicans via sugar polymers present in the cell wall, such as mannan and β-glucan. Here, we examined whether nucleic acids from C. albicans activate dendritic cells. C. albicans DNA induced interleukin-12p40 (IL-12p40)...

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Main Authors: Miyazato, Akiko, Nakamura, Kiwamu, Yamamoto, Natsuo, Mora-Montes, Héctor M., Tanaka, Misuzu, Abe, Yuzuru, Tanno, Daiki, Inden, Ken, Gang, Xiao, Ishii, Keiko, Takeda, Kiyoshi, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Adachi, Yoshiyuki, Ohno, Naohito, Mitsutake, Kotaro, Gow, Neil A. R., Kaku, Mitsuo, Kawakami, Kazuyoshi
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
主題:
Fungal and Parasitic Infections
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708591/
https://ncbi.nlm.nih.gov/pubmed/19433551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00840-08
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