Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

The innate immune system of humans recognizes the human pathogenic fungus Candida albicans via sugar polymers present in the cell wall, such as mannan and β-glucan. Here, we examined whether nucleic acids from C. albicans activate dendritic cells. C. albicans DNA induced interleukin-12p40 (IL-12p40)...

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Main Authors: Miyazato, Akiko, Nakamura, Kiwamu, Yamamoto, Natsuo, Mora-Montes, Héctor M., Tanaka, Misuzu, Abe, Yuzuru, Tanno, Daiki, Inden, Ken, Gang, Xiao, Ishii, Keiko, Takeda, Kiyoshi, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Adachi, Yoshiyuki, Ohno, Naohito, Mitsutake, Kotaro, Gow, Neil A. R., Kaku, Mitsuo, Kawakami, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708591/
https://ncbi.nlm.nih.gov/pubmed/19433551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00840-08
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