Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

The innate immune system of humans recognizes the human pathogenic fungus Candida albicans via sugar polymers present in the cell wall, such as mannan and β-glucan. Here, we examined whether nucleic acids from C. albicans activate dendritic cells. C. albicans DNA induced interleukin-12p40 (IL-12p40)...

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Détails bibliographiques
Auteurs principaux: Miyazato, Akiko, Nakamura, Kiwamu, Yamamoto, Natsuo, Mora-Montes, Héctor M., Tanaka, Misuzu, Abe, Yuzuru, Tanno, Daiki, Inden, Ken, Gang, Xiao, Ishii, Keiko, Takeda, Kiyoshi, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Adachi, Yoshiyuki, Ohno, Naohito, Mitsutake, Kotaro, Gow, Neil A. R., Kaku, Mitsuo, Kawakami, Kazuyoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708591/
https://ncbi.nlm.nih.gov/pubmed/19433551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00840-08
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