Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

The innate immune system of humans recognizes the human pathogenic fungus Candida albicans via sugar polymers present in the cell wall, such as mannan and β-glucan. Here, we examined whether nucleic acids from C. albicans activate dendritic cells. C. albicans DNA induced interleukin-12p40 (IL-12p40)...

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Bibliografiske detaljer
Main Authors: Miyazato, Akiko, Nakamura, Kiwamu, Yamamoto, Natsuo, Mora-Montes, Héctor M., Tanaka, Misuzu, Abe, Yuzuru, Tanno, Daiki, Inden, Ken, Gang, Xiao, Ishii, Keiko, Takeda, Kiyoshi, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Adachi, Yoshiyuki, Ohno, Naohito, Mitsutake, Kotaro, Gow, Neil A. R., Kaku, Mitsuo, Kawakami, Kazuyoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708591/
https://ncbi.nlm.nih.gov/pubmed/19433551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00840-08
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