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Towards the Development of a Potent and Selective Organoruthenium Mammalian Sterile 20 Kinase Inhibitor
Mammalian sterile 20 (MST1) kinase, a member of the sterile 20 (Ste-20) family of proteins, is a proapoptotic cytosolic kinase that plays an important role in the cellular response to oxidative stress. In this study, we report on the development of a potent and selective MST1 kinase inhibitor based...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708071/ https://ncbi.nlm.nih.gov/pubmed/19226137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8005806 |
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