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Crystal structure of domain–swapped STE20 OSR1 kinase domain
OSR1 (oxidative stress-responsive-1) and SPAK (Ste20/Sps1-related proline/alanine-rich kinase) belong to the GCK-VI subfamily of Ste20 group kinases. OSR1 and SPAK are key regulators of NKCCs (Na(+)/K(+)/2Cl(−) cotransporters) and activated by WNK family members (with-no-lysine kinase), mutations of...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708061/ https://ncbi.nlm.nih.gov/pubmed/19177573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.27 |
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