Structural Comparison of Human Mammalian Ste20-Like Kinases

BACKGROUND: The serine/threonine mammalian Ste-20 like kinases (MSTs) are key regulators of apoptosis, cellular proliferation as well as polarization. Deregulation of MSTs has been associated with disease progression in prostate and colorectal cancer. The four human MSTs are regulated differently by...

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Hauptverfasser: Record, Christopher J., Chaikuad, Apirat, Rellos, Peter, Das, Sanjan, Pike, Ashley C. W., Fedorov, Oleg, Marsden, Brian D., Knapp, Stefan, Lee, Wen Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920948/
https://ncbi.nlm.nih.gov/pubmed/20730082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011905
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