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An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen
Heptameric pores formed by the protective antigen (PA) moiety of anthrax toxin translocate the intracellular effector moieties of the toxin across the endosomal membrane to the cytosol of mammalian cells. We devised a protocol to characterize the effects of individual mutations in a single subunit o...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708049/ https://ncbi.nlm.nih.gov/pubmed/19165720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.35 |
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