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OptGraft: A computational procedure for transferring a binding site onto an existing protein scaffold
One of the many challenging tasks of protein design is the introduction of a completely new function into an existing protein scaffold. In this study, we introduce a new computational procedure OptGraft for placing a novel binding pocket onto a protein structure so as its geometry is minimally pertu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708043/ https://ncbi.nlm.nih.gov/pubmed/19177362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2 |
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