Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABA(A) receptors

BACKGROUND AND PURPOSE: The neurosteroid, dehydroepiandrosterone sulphate (DHEAS) and its non-sulphated form, DHEA, are considered as crucial endogenous modulators of a number of important physiological events. Evidence suggests that DHEAS and DHEA modulate central nervous system-related functions b...

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Detalhes bibliográficos
Main Authors: Yoon, Seo-Yeon, Roh, Dae-Hyun, Seo, Hyoung-Sig, Kang, Suk-Yun, Han, Ho-Jae, Beitz, Alvin J, Lee, Jang-Hern
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707978/
https://ncbi.nlm.nih.gov/pubmed/19422393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00197.x
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