Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity

The polymorphism rs2569190 within the CD14 endotoxin (lipopolysaccharide, LPS) receptor gene is associated with various disease conditions that are assumed to rely on endotoxin sensitivity. In vitro experiments suggest that the T allele sensitizes the host for exogenous or endogenous LPS via an enha...

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Библиографические подробности
Главные авторы: Mertens, Jasmin, Bregadze, Rusudan, Mansur, Ashham, Askar, Eva, Bickeböller, Heike, Ramadori, Giuliano, Mihm, Sabine
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2009
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707953/
https://ncbi.nlm.nih.gov/pubmed/19468702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0479-7
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