Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity

The polymorphism rs2569190 within the CD14 endotoxin (lipopolysaccharide, LPS) receptor gene is associated with various disease conditions that are assumed to rely on endotoxin sensitivity. In vitro experiments suggest that the T allele sensitizes the host for exogenous or endogenous LPS via an enha...

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Bibliographic Details
Main Authors: Mertens, Jasmin, Bregadze, Rusudan, Mansur, Ashham, Askar, Eva, Bickeböller, Heike, Ramadori, Giuliano, Mihm, Sabine
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2009
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707953/
https://ncbi.nlm.nih.gov/pubmed/19468702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0479-7
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