Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity

The polymorphism rs2569190 within the CD14 endotoxin (lipopolysaccharide, LPS) receptor gene is associated with various disease conditions that are assumed to rely on endotoxin sensitivity. In vitro experiments suggest that the T allele sensitizes the host for exogenous or endogenous LPS via an enha...

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Hlavní autoři: Mertens, Jasmin, Bregadze, Rusudan, Mansur, Ashham, Askar, Eva, Bickeböller, Heike, Ramadori, Giuliano, Mihm, Sabine
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707953/
https://ncbi.nlm.nih.gov/pubmed/19468702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0479-7
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