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Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats

We show that human embryonic stem cell-derived dopaminergic neurons survived transplantation to the neurotoxin 6-hydroxydopamine-lesioned rat striatum and, in combination with the cells newly differentiated from their progenitors, contributed to locomotive function recovery at 5 months. The animal b...

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Detalhes bibliográficos
Main Authors: Yang, Dali, Zhang, Zhi-Jian, Oldenburg, Michael, Ayala, Melvin, Zhang, Su-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707927/
https://ncbi.nlm.nih.gov/pubmed/17951220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2007-0494
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