Autologous mesenchymal stem cell–derived dopaminergic neurons function in parkinsonian macaques

A cell-based therapy for the replacement of dopaminergic neurons has been a long-term goal in Parkinson’s disease research. Here, we show that autologous engraftment of A9 dopaminergic neuron-like cells induced from mesenchymal stem cells (MSCs) leads to long-term survival of the cells and restorati...

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Detalhes bibliográficos
Main Authors: Hayashi, Takuya, Wakao, Shohei, Kitada, Masaaki, Ose, Takayuki, Watabe, Hiroshi, Kuroda, Yasumasa, Mitsunaga, Kanae, Matsuse, Dai, Shigemoto, Taeko, Ito, Akihito, Ikeda, Hironobu, Fukuyama, Hidenao, Onoe, Hirotaka, Tabata, Yasuhiko, Dezawa, Mari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533267/
https://ncbi.nlm.nih.gov/pubmed/23202734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62516
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