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Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing
West Nile virus (WNV), a mosquito-transmitted single-stranded RNA (ssRNA) flavivirus, causes human disease of variable severity. We investigated Toll-like receptor 7-deficient (Tlr7(−/−)) and myeloid differentiation factor 88-deficient (Myd88(−/−)) mice, which both have defective recognition of ssRN...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707901/ https://ncbi.nlm.nih.gov/pubmed/19200759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.11.012 |
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