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Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect against Type 1 Diabetes

Genome-wide association studies (GWAS) are widely used to map genomic regions contributing to common human diseases but they often do not identify the precise causative genes and sequence variants. To identify causative type 1 diabetes (T1D) variants we re-sequenced exons and splice sites of ten can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nejentsev, Sergey, Walker, Neil, Riches, David, Egholm, Michael, Todd, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707798/
https://ncbi.nlm.nih.gov/pubmed/19264985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1167728
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