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Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect against Type 1 Diabetes

Genome-wide association studies (GWAS) are widely used to map genomic regions contributing to common human diseases but they often do not identify the precise causative genes and sequence variants. To identify causative type 1 diabetes (T1D) variants we re-sequenced exons and splice sites of ten can...

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Detalhes bibliográficos
Main Authors: Nejentsev, Sergey, Walker, Neil, Riches, David, Egholm, Michael, Todd, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707798/
https://ncbi.nlm.nih.gov/pubmed/19264985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1167728
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