Carriers of rare missense variants in IFIH1 are protected from psoriasis

Testing of ~25,000 putative functional single nucleotide polymorphisms (SNPs) across the human genome in a genetic association study has identified three psoriasis genes, IL12B, IL23R and IL13. We now report evidence for the association of psoriasis risk with missense SNPs in the interferon induced...

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Detalhes bibliográficos
Main Authors: Li, Yonghong, Liao, Wilson, Cargill, Michele, Chang, Monica, Matsunami, Nori, Feng, Bingjian, Poon, Annie, Duffin, Kristina Callis, Catanese, Joseph J., Bowcock, Ann M., Leppert, Mark F., Kwok, Pui-Yan, Krueger, Gerald G., Begovich, Ann B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680368/
https://ncbi.nlm.nih.gov/pubmed/20668468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.214
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