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Remission of Invasive, Cancer Stem-Like Glioblastoma Xenografts Using Lentiviral Vector-Mediated Suicide Gene Therapy

BACKGROUND: Glioblastoma is the most frequent and most malignant primary brain tumor with a poor prognosis. The translation of therapeutic strategies for glioblastoma from the experimental phase into the clinic has been limited by insufficient animal models, which lack important features of human tu...

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Autori principali: Huszthy, Peter C., Giroglou, Tsanan, Tsinkalovsky, Oleg, Euskirchen, Philipp, Skaftnesmo, Kai Ove, Bjerkvig, Rolf, von Laer, Dorothee, Miletic, Hrvoje
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707627/
https://ncbi.nlm.nih.gov/pubmed/19617915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006314
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