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Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression

Transplantation of glioblastoma patient biopsy spheroids to the brain of T cell-compromised Rowett (nude) rats has been established as a representative animal model for human GBMs, with a tumor take rate close to 100%. In immunocompetent littermates however, primary human GBM tissue is invariably re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huszthy, Peter C., Sakariassen, Per Ø., Espedal, Heidi, Brokstad, Karl A., Bjerkvig, Rolf, Miletic, Hrvoje
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546393/
https://ncbi.nlm.nih.gov/pubmed/26291724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136089
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