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Accounting for uncertainty when assessing association between copy number and disease: a latent class model

BACKGROUND: Copy number variations (CNVs) may play an important role in disease risk by altering dosage of genes and other regulatory elements, which may have functional and, ultimately, phenotypic consequences. Therefore, determining whether a CNV is associated or not with a given disease might be...

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Detalhes bibliográficos
Main Authors: González, Juan R, Subirana, Isaac, Escaramís, Geòrgia, Peraza, Solymar, Cáceres, Alejandro, Estivill, Xavier, Armengol, Lluís
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707368/
https://ncbi.nlm.nih.gov/pubmed/19500389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-172
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