ATP-dependent Proteases Differ Substantially in Their Ability to Unfold Globular Proteins

ATP-dependent proteases control the concentrations of hundreds of regulatory proteins and remove damaged or misfolded proteins from cells. They select their substrates primarily by recognizing sequence motifs or covalent modifications. Once a substrate is bound to the protease, it has to be unfolded...

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Detalhes bibliográficos
Main Authors: Koodathingal, Prakash, Jaffe, Neil E., Kraut, Daniel A., Prakash, Sumit, Fishbain, Susan, Herman, Christophe, Matouschek, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707231/
https://ncbi.nlm.nih.gov/pubmed/19383601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900783200
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