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Molecular Determinants of the Interaction between Clostridium perfringens Enterotoxin Fragments and Claudin-3
Clostridium perfringens enterotoxin (CPE) binds to the extracellular loop 2 of a subset of claudins, e.g. claudin-3. Here, the molecular mechanism of the CPE-claudin interaction was analyzed. Using peptide arrays, recombinant CPE-(116–319) bound to loop 2 peptides of mouse claudin-3, -6, -7, -9, and...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707212/ https://ncbi.nlm.nih.gov/pubmed/19429681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008623 |
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