Platelets from Diabetic Pigs Exhibit Hypersensitivity to Thrombin

Responses of platelets from diabetic and diabetic–hyperlipidemic pigs were studied. Pigs were made diabetic with single dose of alloxan, which acts by selectively destroying insulin-producing pancreatic β cells thus inducing type 1 diabetes. Pigs were kept for 1 or 12 wk, during which thrombin-induc...

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Main Authors: Shukla, Shivendra D, Kansra, Sanjay V, Reddy, MA, Shukla, Sundeep M, Klachko, David M, Sturek, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Association for Laboratory Animal Science 2008
Teme:
Pig Model
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707134/
https://ncbi.nlm.nih.gov/pubmed/19004374
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