3,3′-Diindolylmethane Induces a G(1) Arrest in Human Prostate Cancer Cells Irrespective of Androgen Receptor and p53 Status

3,3′-Diindolylmethane (DIM) is a potential chemopreventive phytochemical derived from Brassica vegetables. In this study we characterized the effect of DIM on cell cycle regulation in both androgen dependent LNCaP and androgen receptor negative-p53 mutant DU145 human prostate cancer cells. DIM had a...

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Bibliographic Details
Main Authors: Vivar, Omar I., Lin, Chia-Lei, Firestone, Gary L., Bjeldanes, Leonard F.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706920/
https://ncbi.nlm.nih.gov/pubmed/19433067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.05.008
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