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3,3′-Diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells

3,3′-Diindolylmethane (DIM), an indole derivative from vegetables of the Brassica genus, has antiproliferative activity in breast cancer cells. Part of this activity is thought to be due to DIM inhibition of Akt signaling, but an upstream mechanism of DIM-induced Akt inhibition has not been describe...

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Bibliographic Details
Main Authors: Nicastro, Holly L., Firestone, Gary L., Bjeldanes, Leonard F.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808088/
https://ncbi.nlm.nih.gov/pubmed/23968581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2013.05.004
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