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RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites
Mutations affecting the BRCT domains of the breast cancer–associated tumor suppressor BRCA1 disrupt the recruitment of this protein to DNA double-strand breaks (DSBs). The molecular structures at DSBs recognized by BRCA1 are presently unknown. We report the interaction of the BRCA1 BRCT domain with...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706583/ https://ncbi.nlm.nih.gov/pubmed/17525341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1139516 |
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