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RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites

Mutations affecting the BRCT domains of the breast cancer–associated tumor suppressor BRCA1 disrupt the recruitment of this protein to DNA double-strand breaks (DSBs). The molecular structures at DSBs recognized by BRCA1 are presently unknown. We report the interaction of the BRCA1 BRCT domain with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sobhian, Bijan, Shao, Genze, Lilli, Dana R., Culhane, Aedín C., Moreau, Lisa A., Xia, Bing, Livingston, David M., Greenberg, Roger A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706583/
https://ncbi.nlm.nih.gov/pubmed/17525341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1139516
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