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Diverse functions of RNase L and implications in pathology

The endoribonuclease L (RNase L) is the effector of the 2–5A system, a major enzymatic pathway involved in the molecular mechanism of interferons (IFN). RNase L is a very unusual nuclease with a complex mechanism of regulation. It is a latent enzyme, expressed in nearly every mammalian cell type. It...

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Detalhes bibliográficos
Main Authors: Bisbal, Catherine, Silverman, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706398/
https://ncbi.nlm.nih.gov/pubmed/17400356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2007.02.006
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