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Homology Modeling and Site-directed Mutagenesis to Identify Selective Inhibitors of Endothelin-Converting Enzyme-2
Endothelin-converting enzyme-2 (ECE-2), a member of M13 family of zinc metallopeptidases, has previously been shown to process a number of neuropeptides including those derived from prodynorphin, proenkephalin, proSAAS and amyloid precursor protein. ECE-2, unlike ECE-1, exhibits restricted neuroendo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706147/ https://ncbi.nlm.nih.gov/pubmed/18507370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm7015478 |
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