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Residues affecting the chloride regulation and substrate selectivity of the angiotensin‐converting enzymes (ACE and ACE2) identified by site‐directed mutagenesis
Angiotensin‐converting enzyme (ACE) and its homologue angiotensin‐converting enzyme 2 (ACE2) are critical counter‐regulatory enzymes of the renin–angiotensin system, and have been implicated in cardiac function, renal disease, diabetes, atherosclerosis and acute lung injury. Both ACE and ACE2 have c...
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| Publicado en: | FEBS J |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163990/ https://ncbi.nlm.nih.gov/pubmed/19021774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06733.x |
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