Identification of critical active‐site residues in angiotensin‐converting enzyme‐2 (ACE2) by site‐directed mutagenesis

Angiotensin‐converting enzyme‐2 (ACE2) may play an important role in cardiorenal disease and it has also been implicated as a cellular receptor for the severe acute respiratory syndrome (SARS) virus. The ACE2 active‐site model and its crystal structure, which was solved recently, highlighted key dif...

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Vydáno v:FEBS J
Hlavní autoři: Guy, Jodie L., Jackson, Richard M., Jensen, Hanne A., Hooper, Nigel M., Turner, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Ltd 2005
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164114/
https://ncbi.nlm.nih.gov/pubmed/16008552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2005.04756.x
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