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A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle

A chronic increase in physical activity and (or) endurance training can improve insulin sensitivity in insulin-resistant skeletal muscle. Cellular mechanisms responsible for the development of insulin resistance are unclear, though one proposed mechanism is that nutrient overload chronically increas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Glynn, Erin L., Lujan, Heidi L., Kramer, Victoria J., Drummond, Micah J., DiCarlo, Stephen E., Rasmussen, Blake B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706125/
https://ncbi.nlm.nih.gov/pubmed/18347658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/h07-149
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