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Paraplegia increases skeletal muscle autophagy

INTRODUCTION: Paraplegia results in significant skeletal muscle atrophy through increases in skeletal muscle protein breakdown. Recent work has identified a novel SIRT1-p53 pathway that is capable of regulating autophagy and protein breakdown. METHODS: Soleus muscle was collected from 6 male Sprague...

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Detalhes bibliográficos
Main Authors: Fry, Christopher S., Drummond, Micah J., Lujan, Heidi L., DiCarlo, Stephen E., Rasmussen, Blake B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471789/
https://ncbi.nlm.nih.gov/pubmed/23055316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.23423
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