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In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. We previously sequenced 24 cancer genes in those cell lines. Eleven of the genes were found to be mutated in three or more of the lines. Using a ph...

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Detalhes bibliográficos
Main Authors: Ikediobi, Ogechi N., Reimers, Mark, Durinck, Steffen, Blower, Paul E., Futreal, Andrew P., Stratton, Michael R., Weinstein, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705835/
https://ncbi.nlm.nih.gov/pubmed/18524847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2308
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