Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury

Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form (r-Hu-EPO) is directly injected into ischemic rodent brain. We observed abundant expression of the EPO receptor at brain capillaries, which could provide a route for circu...

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Autores principales: Brines, Michael L., Ghezzi, Pietro, Keenan, Sonja, Agnello, Davide, de Lanerolle, Nihal C., Cerami, Carla, Itri, Loretta M., Cerami, Anthony
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC27058/
https://ncbi.nlm.nih.gov/pubmed/10984541
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