A Comprehensive Analysis of the Structure-Function Relationship in Proteins Based on Local Structure Similarity

BACKGROUND: Sequence similarity to characterized proteins provides testable functional hypotheses for less than 50% of the proteins identified by genome sequencing projects. With structural genomics it is believed that structural similarities may give functional hypotheses for many of the remaining...

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Main Authors: Hvidsten, Torgeir R., Lægreid, Astrid, Kryshtafovych, Andriy, Andersson, Gunnar, Fidelis, Krzysztof, Komorowski, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705683/
https://ncbi.nlm.nih.gov/pubmed/19603073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006266
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