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Using multi-data hidden Markov models trained on local neighborhoods of protein structure to predict residue–residue contacts

Motivation:Correct prediction of residue–residue contacts in proteins that lack good templates with known structure would take ab initio protein structure prediction a large step forward. The lack of correct contacts, and in particular long-range contacts, is considered the main reason why these met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Björkholm, Patrik, Daniluk, Pawel, Kryshtafovych, Andriy, Fidelis, Krzysztof, Andersson, Robin, Hvidsten, Torgeir R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677742/
https://ncbi.nlm.nih.gov/pubmed/19289446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp149
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