FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

The liver plays a crucial role in mobilizing energy during nutritional deprivation. During the early stages of fasting, hepatic glycogenolysis is a primary energy source. As fasting progresses and glycogen stores are depleted, hepatic gluconeogenesis and ketogenesis become major energy sources. Here...

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Main Authors: Potthoff, Matthew J., Inagaki, Takeshi, Satapati, Santhosh, Ding, Xunshan, He, Tianteng, Goetz, Regina, Mohammadi, Moosa, Finck, Brian N., Mangelsdorf, David J., Kliewer, Steven A., Burgess, Shawn C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705613/
https://ncbi.nlm.nih.gov/pubmed/19541642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904187106
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