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ClpXP protease degrades the cytoskeletal protein, FtsZ, and modulates FtsZ polymer dynamics

FtsZ is the major cytoskeletal protein in bacteria and a tubulin homologue. It polymerizes and forms a ring where constriction occurs to divide the cell. We found that FtsZ is degraded by E. coli ClpXP, an ATP-dependent protease. In vitro, ClpXP degrades both FtsZ protomers and polymers; however, po...

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Detalhes bibliográficos
Main Authors: Camberg, Jodi L., Hoskins, Joel R., Wickner, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705540/
https://ncbi.nlm.nih.gov/pubmed/19541655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904886106
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