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Estimating the posterior probability that genome-wide association findings are true or false

Motivation: A limitation of current methods used to declare significance in genome-wide association studies (GWAS) is that they do not provide clear information about the probability that GWAS findings are true of false. This lack of information increases the chance of false discoveries and may resu...

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Detalhes bibliográficos
Main Authors: Bukszár, József, McClay, Joseph L., van den Oord, Edwin J. C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705227/
https://ncbi.nlm.nih.gov/pubmed/19420056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp305
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