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Estimating Effect Sizes in Genome-Wide Association Studies

Knowledge about the proportion of markers without effects (p(0)) and the effect sizes in large scale genetic studies is important to understand the basic properties of the data and for applications such as the control of false discoveries and designing adequately powered replication studies. Many p(...

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Autors principals: Bukszár, József, van den Oord, Edwin J. C. G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923086/
https://ncbi.nlm.nih.gov/pubmed/20052610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-009-9321-9
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