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Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells

The superantigen SEA causes non-specific hyperactivation of T and B cells at low concentrations. Studies of mutants or soluble proteins suggest SEA is bivalent for its ligand, MHC class II. However, the interaction between these molecules on intact cells is unknown. On primary mouse B cells expressi...

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Autors principals: Narayan, Kedar, Perkins, Edward M., Murphy, Gavin E., Dalai, Sarat K., Edidin, Michael, Subramaniam, Sriram, Sadegh-Nasseri, Scheherazade
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705189/
https://ncbi.nlm.nih.gov/pubmed/19587800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006188
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