Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells

The superantigen SEA causes non-specific hyperactivation of T and B cells at low concentrations. Studies of mutants or soluble proteins suggest SEA is bivalent for its ligand, MHC class II. However, the interaction between these molecules on intact cells is unknown. On primary mouse B cells expressi...

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Detalhes bibliográficos
Main Authors: Narayan, Kedar, Perkins, Edward M., Murphy, Gavin E., Dalai, Sarat K., Edidin, Michael, Subramaniam, Sriram, Sadegh-Nasseri, Scheherazade
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705189/
https://ncbi.nlm.nih.gov/pubmed/19587800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006188
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