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Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV

Although antiretroviral therapies have been effective in decreasing active viral loads in AIDS patients, the persistence of latent viral reservoirs prevents eradication of the virus. Prostratin and DPP (12-deoxyphorbol-13-phenylacetate) activate the latent virus and thus represent promising adjuvant...

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Main Authors: Wender, Paul A., Kee, Jung-Min, Warrington, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704988/
https://ncbi.nlm.nih.gov/pubmed/18451298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1154690
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